Reactome | Activation of ISG15 by UBA7 E1 ligase

Schema > Reaction > Entries

Activation of ISG15 by UBA7 E1 ligase Show undefined attributes

catalystActivity	[CatalystActivity:10138841] ubiquitin-protein transferase activity of UBA7 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10138843
displayName	Activation of ISG15 by UBA7 E1 ligase
eventOf	[Pathway:R-CFA-1169408] ISG15 antiviral mechanism - Canis familiaris
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1169397] Activation of ISG15 by UBA7 E1 ligase - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [EntityWithAccessionedSequence:R-CFA-936550] CDHR4 [cytosol] [EntityWithAccessionedSequence:R-CFA-936552] ISG15 [cytosol]
isInDisease	false
isInferred	true
name	Activation of ISG15 by UBA7 E1 ligase
output	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-CFA-1169390] ISG15:UBA7 [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1169397
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-1169408] ISG15 antiviral mechanism
(inferredTo)	[Reaction:R-HSA-1169397] Activation of ISG15 by UBA7 E1 ligase

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