Reactome | RAB GEFs exchange GTP for GDP on RABs

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RAB GEFs exchange GTP for GDP on RABs Show undefined attributes

created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10818155
displayName	RAB GEFs exchange GTP for GDP on RABs
eventOf	[Pathway:R-CEL-9007101] Rab regulation of trafficking - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-CEL-8877475] TRAPPC complexes exchange GTP for GDP on RAB1 - Caenorhabditis elegans [Reaction:R-CEL-8875318] RAB3 GEFs exchange GTP for GDP on RAB3A - Caenorhabditis elegans [Reaction:R-CEL-8875320] RAB5 GEFs exchange GTP for GDP on RAB5 - Caenorhabditis elegans [Reaction:R-CEL-8876193] RIC1-RGP1 exchanges GTP for GDP on RAB6 - Caenorhabditis elegans [Reaction:R-CEL-8877451] MON1:CCZ1 exchanges GTP for GDP on RAB7 - Caenorhabditis elegans [Reaction:R-CEL-8876190] RAB8 GEFs exchange GTP for GDP on RAB8 - Caenorhabditis elegans [Reaction:R-CEL-8876188] DENND4s exchange GTP for GDP on RAB10 - Caenorhabditis elegans [Reaction:R-CEL-8876615] RAB13 GEFs exchange GTP for GDP on RAB13 - Caenorhabditis elegans [Reaction:R-CEL-8876616] DENND6A,B exchange GTP for GDP on RAB14 - Caenorhabditis elegans [Reaction:R-CEL-8876837] RAB21 GEFs exchange GTP for GDP on RAB21 - Caenorhabditis elegans [Reaction:R-CEL-8877308] MADD exchanges GTP for GDP on RAB27 - Caenorhabditis elegans [Reaction:R-CEL-8933446] Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling - Caenorhabditis elegans [Reaction:R-CEL-8877612] DENND1s exchange GTP for GDP on RAB35 - Caenorhabditis elegans [Reaction:R-CEL-8877813] DENND5A,B exchange GTP for GDP on RAB39 - Caenorhabditis elegans [Reaction:R-CEL-8877998] RAB3GAP1:RAB3GAP2 exchanges GTP for GDP on RAB18 - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-8876198] RAB GEFs exchange GTP for GDP on RABs - Homo sapiens
isInDisease	false
isInferred	true
name	RAB GEFs exchange GTP for GDP on RABs
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8876198
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-9007101] Rab regulation of trafficking
(inferredTo)	[Pathway:R-HSA-8876198] RAB GEFs exchange GTP for GDP on RABs

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