Reactome | PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]

Schema > Complex > Entries

PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:10806492] phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity of PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CEL-8868648] SYNJ hydrolyze PI(4,5)P2 to PI(4)P - Caenorhabditis elegans
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10806489
displayName	PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
hasComponent	[Complex:R-CEL-8868234] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] [DefinedSet:R-CEL-1806173] SYNJs,OCRL [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8868634] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - Homo sapiens
name	PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs
producedByEvent	[Reaction:R-CEL-8868651] Endophilins recruit synaptojanins to the clathrin-coated pit - Caenorhabditis elegans
schemaClass	Complex
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8868634
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-CEL-8868648] SYNJ hydrolyze PI(4,5)P2 to PI(4)P
(physicalEntity)	[CatalystActivity:10806492] phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity of PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
(output)	[Reaction:R-CEL-8868651] Endophilins recruit synaptojanins to the clathrin-coated pit
(inferredTo)	[Complex:R-HSA-8868634] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]

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