Reactome | AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG

Schema > Reaction > Entries

AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG Show undefined attributes

catalystActivity	[CatalystActivity:10796487] 2-acylglycerol O-acyltransferase activity of AWAT2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:70101] cytosol
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10796489
displayName	AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG
eventOf	[Pathway:R-CEL-1482883] Acyl chain remodeling of DAG and TAG - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 - Caenorhabditis elegans [Reaction:R-CEL-1482889] DAG is acylated to TAG by DGAT1/2 - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG - Homo sapiens
input	[SimpleEntity:R-ALL-6782195] Acyl-CoA [endoplasmic reticulum membrane] [SimpleEntity:R-ALL-5696449] MAG [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
name	AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG
output	[SimpleEntity:R-ALL-76194] CoA-SH [cytosol] [SimpleEntity:R-ALL-1500596] DAG [endoplasmic reticulum membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5696448
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1482883] Acyl chain remodeling of DAG and TAG
(precedingEvent)	[Reaction:R-CEL-1482811] DAG is hydrolyzed to 2-MAG by PNPLA2/3 [Reaction:R-CEL-1482889] DAG is acylated to TAG by DGAT1/2
(inferredTo)	[Reaction:R-HSA-5696448] AWAT2 transfers acyl group from acyl-CoA to MAG, forming DAG