Reactome | Phosphorylated AMPK binds AMP

Schema > Reaction > Entries

Phosphorylated AMPK binds AMP Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10759026
displayName	Phosphorylated AMPK binds AMP
eventOf	[Pathway:R-CEL-380972] Energy dependent regulation of mTOR by LKB1-AMPK - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-200423] pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis - Caenorhabditis elegans [Reaction:R-CEL-447074] AMPK phosphorylates Raptor in the mTORC1 complex - Caenorhabditis elegans [Reaction:R-CEL-5673768] p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-380930] Phosphorylated AMPK binds AMP - Homo sapiens
input	[SimpleEntity:R-ALL-76577] AMP [cytosol] [Complex:R-CEL-380934] p-AMPK heterotrimer [cytosol]
isInDisease	false
isInferred	true
name	Phosphorylated AMPK binds AMP
output	[Complex:R-CEL-380931] p-AMPK heterotrimer:AMP [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-380930
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-CEL-200423] pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis [Reaction:R-CEL-447074] AMPK phosphorylates Raptor in the mTORC1 complex [Reaction:R-CEL-5673768] p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex
(hasEvent)	[Pathway:R-CEL-380972] Energy dependent regulation of mTOR by LKB1-AMPK
(inferredTo)	[Reaction:R-HSA-380930] Phosphorylated AMPK binds AMP

© 2024 Reactome

Cite Us!