Reactome | SYNJ hydrolyze PI(4,5)P2 to PI(4)P

Schema > Reaction > Entries

SYNJ hydrolyze PI(4,5)P2 to PI(4)P Show undefined attributes

catalystActivity	[CatalystActivity:10294882] phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity of PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10294884
displayName	SYNJ hydrolyze PI(4,5)P2 to PI(4)P
eventOf	[Pathway:R-BTA-8856828] Clathrin-mediated endocytosis - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8868661] Dynamin-mediated GTP hydrolysis promotes vesicle scission - Bos taurus
inferredFrom	[Reaction:R-HSA-8868648] SYNJ hydrolyze PI(4,5)P2 to PI(4)P - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [Complex:R-BTA-8868634] PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
isInDisease	false
isInferred	true
name	SYNJ hydrolyze PI(4,5)P2 to PI(4)P
output	[SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-BTA-8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane]
precedingEvent	[Reaction:R-BTA-8868651] Endophilins recruit synaptojanins to the clathrin-coated pit - Bos taurus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8868648
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8856828] Clathrin-mediated endocytosis
(precedingEvent)	[Reaction:R-BTA-8868661] Dynamin-mediated GTP hydrolysis promotes vesicle scission
(inferredTo)	[Reaction:R-HSA-8868648] SYNJ hydrolyze PI(4,5)P2 to PI(4)P