Reactome | TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest

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TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Show undefined attributes

created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10310672
displayName	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
eventOf	[Pathway:R-BTA-6791312] TP53 Regulates Transcription of Cell Cycle Genes - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-187934] Inactivation of Cyclin A:Cdk2 complexes by p27/p21 - Bos taurus [Reaction:R-BTA-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21 - Bos taurus [Reaction:R-BTA-8952996] E2F7 forms homodimers - Bos taurus [Reaction:R-BTA-8953013] E2F7 binds E2F8 - Bos taurus [Reaction:R-BTA-8953037] E2F8 forms homodimers - Bos taurus
inferredFrom	[Pathway:R-HSA-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest - Homo sapiens
isInDisease	false
isInferred	true
name	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-6804116
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-6791312] TP53 Regulates Transcription of Cell Cycle Genes
(inferredTo)	[Pathway:R-HSA-6804116] TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest

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