Reactome | Activated FGFR1c bound to FGF23:Klotho [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10210791
displayName	Activated FGFR1c bound to FGF23:Klotho [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-190915] HS [extracellular region] 2 × [Complex:R-BTA-190208] Klotho bound to FGF23 [plasma membrane] 2 × [EntityWithAccessionedSequence:R-BTA-190434] phospho-p-8Y-FGFR1c [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-500333] Activated FGFR1c bound to FGF23:Klotho [plasma membrane] - Homo sapiens
memberOf	[DefinedSet:R-BTA-190352] Activated FGFR [plasma membrane] - Bos taurus [DefinedSet:R-BTA-5654170] Activated FGFR1 [plasma membrane] - Bos taurus
name	Activated FGFR1c bound to FGF23:Klotho
producedByEvent	[Reaction:R-BTA-191062] Autocatalytic phosphorylation of Klotho-bound FGFR1c - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-500333
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(hasMember)	[DefinedSet:R-BTA-190352] Activated FGFR [plasma membrane] [DefinedSet:R-BTA-5654170] Activated FGFR1 [plasma membrane]
(output)	[Reaction:R-BTA-191062] Autocatalytic phosphorylation of Klotho-bound FGFR1c
(inferredTo)	[Complex:R-HSA-500333] Activated FGFR1c bound to FGF23:Klotho [plasma membrane]