Reactome | HS6STs sulfate GlcN at C6 in heparan sulfate/heparin

Schema > Reaction > Entries

HS6STs sulfate GlcN at C6 in heparan sulfate/heparin Show undefined attributes

catalystActivity	[CatalystActivity:10257569] heparan sulfate 6-O-sulfotransferase activity of HS6STs [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10257571
displayName	HS6STs sulfate GlcN at C6 in heparan sulfate/heparin
eventOf	[Pathway:R-BTA-2022928] HS-GAG biosynthesis - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-2024108] Some HSPGs are secreted to the plasma membrane - Bos taurus
goBiologicalProcess	[GO_BiologicalProcess:19673] heparan sulfate proteoglycan biosynthetic process, enzymatic modification
inferredFrom	[Reaction:R-HSA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin - Homo sapiens
input	[DefinedSet:R-BTA-2076461] HS(5)-PGs [Golgi lumen] [SimpleEntity:R-ALL-741440] PAPS [Golgi lumen]
isInDisease	false
isInferred	true
name	HS6STs sulfate GlcN at C6 in heparan sulfate/heparin
output	[DefinedSet:R-BTA-2076357] HS/HPIN-PGs [Golgi lumen] [SimpleEntity:R-ALL-742343] PAP [Golgi lumen]
precedingEvent	[Reaction:R-BTA-741449] SLC35B2,3 transport cytosolic PAPS to Golgi lumen - Bos taurus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-2076419
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-2022928] HS-GAG biosynthesis
(precedingEvent)	[BlackBoxEvent:R-BTA-2024108] Some HSPGs are secreted to the plasma membrane
(inferredTo)	[Reaction:R-HSA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin