Reactome | 6MP [cytosol]

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6MP [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-DDI-9748991] XDH oxidises 6MP to 6TU - Dictyostelium discoideum [Reaction:R-CEL-9748991] XDH oxidises 6MP to 6TU - Caenorhabditis elegans [Reaction:R-DME-9748991] XDH oxidises 6MP to 6TU - Drosophila melanogaster [Reaction:R-GGA-9748991] XDH oxidises 6MP to 6TU - Gallus gallus [Reaction:R-XTR-9748991] XDH oxidises 6MP to 6TU - Xenopus tropicalis [Reaction:R-SSC-9748991] XDH oxidises 6MP to 6TU - Sus scrofa [Reaction:R-BTA-9748991] XDH oxidises 6MP to 6TU - Bos taurus [Reaction:R-CFA-9748991] XDH oxidises 6MP to 6TU - Canis familiaris [Reaction:R-RNO-9748991] XDH oxidises 6MP to 6TU - Rattus norvegicus [Reaction:R-MMU-9748991] XDH oxidises 6MP to 6TU - Mus musculus [Reaction:R-HSA-9748991] XDH oxidises 6MP to 6TU - Homo sapiens [Reaction:R-GGA-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Gallus gallus [Reaction:R-XTR-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Xenopus tropicalis [Reaction:R-DRE-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Danio rerio [Reaction:R-SSC-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Sus scrofa [Reaction:R-BTA-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Bos taurus [Reaction:R-CFA-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Canis familiaris [Reaction:R-RNO-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Rattus norvegicus [Reaction:R-MMU-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Mus musculus [Reaction:R-HSA-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Homo sapiens [Reaction:R-MMU-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Mus musculus [Reaction:R-RNO-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Rattus norvegicus [Reaction:R-CFA-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Canis familiaris [Reaction:R-BTA-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Bos taurus [Reaction:R-SSC-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Sus scrofa [Reaction:R-DRE-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Danio rerio [Reaction:R-GGA-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Gallus gallus [Reaction:R-CEL-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Caenorhabditis elegans [Reaction:R-DDI-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Dictyostelium discoideum [Reaction:R-PFA-9748951] HPRT1 tetramer transfers phosphoribosyl group to 6MP to form 6TIMP - Plasmodium falciparum [Reaction:R-HSA-9748983] TPMT transfers methyl group to 6MP, forming 6MeMP - Homo sapiens
created	[InstanceEdit:9748997] Jassal, Bijay, 2021-07-29
crossReference	[DatabaseIdentifier:9755269] ChEBI:50667
dbId	9748998
disease	[Disease:9660768] Crohn's disease [Disease:9625953] ulcerative colitis
displayName	6MP [cytosol]
inDisease	true
modified	[InstanceEdit:9755271] Jassal, Bijay, 2021-10-07
name	6MP 6-mercaptopurine Mercaptopurine
producedByEvent	[Reaction:R-CEL-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DME-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-HSA-9748996] GST dimers cleave AZA to 6MP - Homo sapiens [Reaction:R-MMU-9748996] GST dimers cleave AZA to 6MP - Mus musculus [Reaction:R-RNO-9748996] GST dimers cleave AZA to 6MP - Rattus norvegicus [Reaction:R-CFA-9748996] GST dimers cleave AZA to 6MP - Canis familiaris [Reaction:R-BTA-9748996] GST dimers cleave AZA to 6MP - Bos taurus [Reaction:R-SSC-9748996] GST dimers cleave AZA to 6MP - Sus scrofa [Reaction:R-DRE-9748996] GST dimers cleave AZA to 6MP - Danio rerio [Reaction:R-XTR-9748996] GST dimers cleave AZA to 6MP - Xenopus tropicalis [Reaction:R-GGA-9748996] GST dimers cleave AZA to 6MP - Gallus gallus [Reaction:R-DDI-9748996] GST dimers cleave AZA to 6MP - Dictyostelium discoideum [Reaction:R-PFA-9748996] GST dimers cleave AZA to 6MP - Plasmodium falciparum [Reaction:R-HSA-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Homo sapiens [Reaction:R-MMU-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Mus musculus [Reaction:R-RNO-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Rattus norvegicus [Reaction:R-CFA-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Canis familiaris [Reaction:R-BTA-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Bos taurus [Reaction:R-SSC-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Sus scrofa [Reaction:R-DRE-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Danio rerio [Reaction:R-XTR-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-DME-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-CEL-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-DDI-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Dictyostelium discoideum [Reaction:R-PFA-9751024] SLC29A1,2 transport 6MP from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-HSA-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Homo sapiens [Reaction:R-MMU-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Mus musculus [Reaction:R-RNO-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Rattus norvegicus [Reaction:R-CFA-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Canis familiaris [Reaction:R-BTA-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Bos taurus [Reaction:R-SSC-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Sus scrofa [Reaction:R-XTR-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-GGA-9751037] SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol - Gallus gallus
referenceEntity	[ReferenceTherapeutic:9748973] mercaptopurine [Guide to Pharmacology:7226]
schemaClass	ChemicalDrug
stId	R-ALL-9748998

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