Reactome | PDGF:Phospho-PDGF receptor dimer [plasma membrane]

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PDGF:Phospho-PDGF receptor dimer [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-380766] PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] - Rattus norvegicus [Complex:R-RNO-186839] PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-186778] SHP2 binds to the active receptor - Rattus norvegicus [Reaction:R-RNO-382055] Grb7 binds to the active PDGF receptor - Rattus norvegicus [Reaction:R-RNO-382058] Nck binds to the active PDGF receptor - Rattus norvegicus [Reaction:R-RNO-186765] PLC-gamma binds to the active receptor - Rattus norvegicus [Reaction:R-RNO-186819] SH2 domain of Src binds to the active receptor - Rattus norvegicus [Reaction:R-RNO-382056] Crk binds to the active PDGF receptor - Rattus norvegicus [Reaction:R-RNO-186780] PI3-kinase binds to the active receptor - Rattus norvegicus [Reaction:R-RNO-186826] GRB2:SOS1 complex binds to the active receptor - Rattus norvegicus [Reaction:R-RNO-380782] STAT binds to the active receptor - Rattus norvegicus
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	9997488
displayName	PDGF:Phospho-PDGF receptor dimer [plasma membrane]
hasComponent	[DefinedSet:R-RNO-380760] Active PDGF dimers (AA, AB, BB) [extracellular region] [DefinedSet:R-RNO-186821] Phospho- PDGF receptor dimer [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-186811] PDGF:Phospho-PDGF receptor dimer [plasma membrane] - Homo sapiens
name	PDGF:Phospho-PDGF receptor dimer
producedByEvent	[Reaction:R-RNO-1524182] Activated PLC gamma dissociates from the PDGF receptor - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-186811
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-RNO-186778] SHP2 binds to the active receptor [Reaction:R-RNO-382055] Grb7 binds to the active PDGF receptor [Reaction:R-RNO-382058] Nck binds to the active PDGF receptor [Reaction:R-RNO-186765] PLC-gamma binds to the active receptor [Reaction:R-RNO-380782] STAT binds to the active receptor [Reaction:R-RNO-186819] SH2 domain of Src binds to the active receptor [Reaction:R-RNO-382056] Crk binds to the active PDGF receptor [Reaction:R-RNO-186780] PI3-kinase binds to the active receptor [Reaction:R-RNO-186826] GRB2:SOS1 complex binds to the active receptor
(hasComponent)	[Complex:R-RNO-186839] PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] [Complex:R-RNO-381956] PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] [Complex:R-RNO-381954] PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] [Complex:R-RNO-1524184] PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] [Complex:R-RNO-186795] PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] [Complex:R-RNO-380766] PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] [Complex:R-RNO-186831] PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] [Complex:R-RNO-381955] PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] [Complex:R-RNO-186827] PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] [Complex:R-RNO-186789] PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane]
(output)	[Reaction:R-RNO-1524182] Activated PLC gamma dissociates from the PDGF receptor
(inferredTo)	[Complex:R-HSA-186811] PDGF:Phospho-PDGF receptor dimer [plasma membrane]

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