Reactome | CBL autoubiquitinates

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CBL autoubiquitinates Show undefined attributes

catalystActivity	[CatalystActivity:9956348] ubiquitin protein ligase activity of p-Y700,Y731,Y774-CBL [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9956350
displayName	CBL autoubiquitinates
eventOf	[Pathway:R-MMU-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-8848829] CBL autoubiquitinates - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-912656] phospho-p-Y700,Y731,Y774-CBL [cytosol] 3 × [DefinedSet:R-MMU-113595] Ub [cytosol]
isInDisease	false
isInferred	true
name	CBL autoubiquitinates
output	[EntityWithAccessionedSequence:R-MMU-8848826] phospho-PolyUb,p-Y700,Y731,Y774-CBL [cytosol]
precedingEvent	[Reaction:R-MMU-8848818] PTK6 phosphorylates CBL - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8848829
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
(inferredTo)	[Reaction:R-HSA-8848829] CBL autoubiquitinates