Reactome | PTK6 binds DOK1

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PTK6 binds DOK1 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9956333
displayName	PTK6 binds DOK1
eventOf	[Pathway:R-MMU-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8848776] PTK6 phosphorylates DOK1 - Mus musculus
inferredFrom	[Reaction:R-HSA-8848774] PTK6 binds DOK1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-74763] Dok1 [cytosol] [EntityWithAccessionedSequence:R-MMU-9709374] p-Y342-Ptk6 [cytosol]
isInDisease	false
isInferred	true
name	PTK6 binds DOK1
output	[Complex:R-MMU-8848773] p-Y342-PTK6:DOK1 [cytosol]
precedingEvent	[Reaction:R-MMU-8848005] ERBB2 promotes PTK6 autophosphorylation - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8848774
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
(precedingEvent)	[Reaction:R-MMU-8848776] PTK6 phosphorylates DOK1
(inferredTo)	[Reaction:R-HSA-8848774] PTK6 binds DOK1