Reactome | Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases

Schema > BlackBoxEvent > Entries

Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases Show undefined attributes

catalystActivity	[CatalystActivity:9906770] aminopeptidase activity of IFN gamma stimulated aminopeptidases [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9906772
displayName	Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases
eventOf	[Pathway:R-MMU-983168] Antigen processing: Ubiquitination & Proteasome degradation - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-983144] Transport of Antigen peptide in to ER - Mus musculus [BlackBoxEvent:R-MMU-8940641] THOP1 cleaves oligopeptide fragment (8-16aa) - Mus musculus
inferredFrom	[BlackBoxEvent:R-HSA-983162] Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases - Homo sapiens
input	[SimpleEntity:R-ALL-983036] precursor peptide fragment (>16 aa) [cytosol]
isInDisease	false
isInferred	true
name	Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases
output	[SimpleEntity:R-ALL-8942986] L-amino acid [cytosol] [SimpleEntity:R-ALL-983032] oligopeptide fragment (8-16aa) [cytosol]
precedingEvent	[BlackBoxEvent:R-MMU-983150] Proteasomal cleavage of substrate - Mus musculus
releaseDate	2024-03-27
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-983162
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-983168] Antigen processing: Ubiquitination & Proteasome degradation
(precedingEvent)	[BlackBoxEvent:R-MMU-8940641] THOP1 cleaves oligopeptide fragment (8-16aa) [Reaction:R-MMU-983144] Transport of Antigen peptide in to ER
(inferredTo)	[BlackBoxEvent:R-HSA-983162] Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases

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