Reactome | Interaction of PECAM-1 and SHP-1

Schema > Reaction > Entries

Interaction of PECAM-1 and SHP-1 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9885886
displayName	Interaction of PECAM-1 and SHP-1
eventOf	[Pathway:R-MMU-210990] PECAM1 interactions - Mus musculus [Pathway:R-MMU-432142] Platelet sensitization by LDL - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-210277] Interaction of PECAM-1 and SHP-1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-210007] phospho-Pecam1 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-197938] PTPN6 [cytosol]
isInDisease	false
isInferred	true
name	Interaction of PECAM-1 and SHP-1
output	[Complex:R-MMU-210221] PECAM-1:SHP-1 complex [plasma membrane]
precedingEvent	[Reaction:R-MMU-210291] Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src - Mus musculus [BlackBoxEvent:R-MMU-435244] PECAM1 is phosphorylated - Mus musculus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-210277
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-432142] Platelet sensitization by LDL [Pathway:R-MMU-210990] PECAM1 interactions
(inferredTo)	[Reaction:R-HSA-210277] Interaction of PECAM-1 and SHP-1

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