Reactome | CDC42:GTP binds CBL:Beta-Pix

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9864362] Wright, Adam, 2024-03-07
dbId	9879364
displayName	CDC42:GTP binds CBL:Beta-Pix
eventOf	[Pathway:R-MMU-182971] EGFR downregulation - Mus musculus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-183094] CDC42:GTP binds CBL:Beta-Pix - Homo sapiens
input	[Complex:R-MMU-182917] Beta-Pix:CDC42:GTP [cytosol] [EntityWithAccessionedSequence:R-MMU-112199] CBL [cytosol]
isInDisease	false
isInferred	true
name	CDC42:GTP binds CBL:Beta-Pix CDC42 lures CBL away from the receptor
output	[Complex:R-MMU-182956] CBL:Beta-Pix:CDC42:GTP [cytosol]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-183094
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-182971] EGFR downregulation
(inferredTo)	[Reaction:R-HSA-183094] CDC42:GTP binds CBL:Beta-Pix

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