Reactome | ub-NFE2L2 [cytosol]

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ub-NFE2L2 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9755498] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol] - Homo sapiens
consumedByEvent	[BlackBoxEvent:R-HSA-8932355] 26S proteasome degrades Ub-NFE2L2 - Homo sapiens
created	[InstanceEdit:9758079] Rothfels, Karen, 2021-11-09
dbId	9758077
displayName	ub-NFE2L2 [cytosol]
endCoordinate	605
hasModifiedResidue	[GroupModifiedResidue:9758080] ubiquitinylated lysine (K48-linked polyubiquitin chain [cytosol]) at unknown position
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-9758077] Nfe2l2 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-9758077] Nfe2l2 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-9758077] NFE2L2 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-9758077] NFE2L2 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-9758077] NFE2L2 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-9758077] nrf2 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-9758077] nfe2l2 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-9758077] ub-NFE2L2 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-9758077] cnc [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-9758077] sknr-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-CEL-9758077-2] skn-1 [cytosol] - Caenorhabditis elegans [DefinedSet:R-CEL-9758077-3] Homologues of ub-NFE2L2 [cytosol] - Caenorhabditis elegans [GenomeEncodedEntity:R-DDI-9758077] Ghost homologue of ub-NFE2L2 [cytosol] - Dictyostelium discoideum [GenomeEncodedEntity:R-SPO-9758077] Ghost homologue of ub-NFE2L2 [cytosol] - Schizosaccharomyces pombe [GenomeEncodedEntity:R-SCE-9758077] Ghost homologue of ub-NFE2L2 [cytosol] - Saccharomyces cerevisiae [GenomeEncodedEntity:R-PFA-9758077] Ghost homologue of ub-NFE2L2 [cytosol] - Plasmodium falciparum
modified	[InstanceEdit:9758126] Rothfels, Karen, 2021-11-09
name	ub-NFE2L2
producedByEvent	[Reaction:R-HSA-9758090] Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation - Homo sapiens
referenceEntity	[ReferenceGeneProduct:60145] UniProt:Q16236 NFE2L2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-9758077
startCoordinate	1

Referrals

(input)	[BlackBoxEvent:R-HSA-8932355] 26S proteasome degrades Ub-NFE2L2
(output)	[Reaction:R-HSA-9758090] Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation
(hasComponent)	[Complex:R-HSA-9755498] ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1 [cytosol]

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