Reactome | MeCP2, a key contributor to neurological disease, activates and represses transcription

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MeCP2, a key contributor to neurological disease, activates and represses transcription Show undefined attributes

author	[Person:8985269] Chahrour, M [Person:2484995] Jung, SY [Person:9021090] Shaw, C [Person:9021093] Zhou, X [Person:9021087] Wong, ST [Person:76752] Qin, J [Person:9017936] Zoghbi, HY
created	[InstanceEdit:9021094] Orlic-Milacic, Marija, 2017-09-13
dbId	9021089
displayName	MeCP2, a key contributor to neurological disease, activates and represses transcription
journal	Science
pages	1224-9
pubMedIdentifier	18511691
schemaClass	LiteratureReference
title	MeCP2, a key contributor to neurological disease, activates and represses transcription
url	http://www.ncbi.nlm.nih.gov/pubmed/18511691
volume	320
year	2008

Referrals

(author)

[Person:76752] Qin, J
[Person:2484995] Jung, SY
[Person:9021087] Wong, ST
[Person:9017936] Zoghbi, HY
[Person:9021090] Shaw, C
[Person:8985269] Chahrour, M
[Person:9021093] Zhou, X

(literatureReference)

[Pathway:R-HSA-8986944] Transcriptional Regulation by MECP2
[Pathway:R-HSA-9022707] MECP2 regulates transcription factors
[Summation:9022127] Based on studies in mice, transcription of the RBFOX1 (A2BP1...
[BlackBoxEvent:R-MMU-9021967] Rbfox1 gene expression is inhibited by Mecp2
[RegulationReference:9642984] Negative gene expression regulation by 'Mecp2:Rbfox1 gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[Summation:9022082] Based on studies in mice, transcription of the MEF2C gene is...
[BlackBoxEvent:R-MMU-9021975] Mef2c gene expression is inhibited by Mecp2
[RegulationReference:9642568] Negative gene expression regulation by 'Mecp2:Mef2c gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[Summation:9022084] Based on studies in mice, MECP2 binds the promoter region of...
[Complex:R-MMU-9021992] Mecp2:Oprk1 gene [nucleoplasm]
[Reaction:R-MMU-9021969] Mecp2 binds Oprk1 gene promoter
[Summation:9021990] Based on studies in mice, MECP2 binds the promoter region of...
[Complex:R-MMU-9021875] Mecp2:Creb1 gene [nucleoplasm]
[Reaction:R-MMU-9021849] Mecp2 binds Creb1 gene promoter
[Summation:9021857] Based on studies in mice, MECP2 binds the promoter region of...
[RegulationReference:9642547] Positive gene expression regulation by 'Mecp2:Creb1 gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[BlackBoxEvent:R-MMU-9021848] Creb1 gene expression is stimulated by Mecp2
[Summation:9021858] Based on studies in mice, transcription of the CREB1 gene is...
[Reaction:R-MMU-9021887] Mecp2 binds Creb1
[Summation:9021891] Based on studies in mice, MECP2 forms a complex with CREB1 (...
[Complex:R-MMU-9022072] Mecp2:Gprin1 gene [nucleoplasm]
[Reaction:R-MMU-9021971] Mecp2 binds Gprin1 gene promoter
[Summation:9022049] Based on studies in mice, MECP2 binds the promoter region of...
[RegulationReference:9642857] Positive gene expression regulation by 'Mecp2:Gprin1 gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[BlackBoxEvent:R-MMU-9021972] Gprin1 gene expression is stimulated by Meco2
[Summation:9022050] Based on studies in mice, MECP2 directly stimulates transcri...
[RegulationReference:9642838] Positive gene expression regulation by 'Mecp2:Oprk1 gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[BlackBoxEvent:R-MMU-9021966] Oprk1 gene expression is stimulated by Mecp2
[Summation:9022006] Based on studies in mice, MECP2 stimulates transcription of ...
[Pathway:R-HSA-9022699] MECP2 regulates neuronal receptors and channels
[RegulationReference:9642059] Positive regulation by 'MECP2 [nucleoplasm]' Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA
[Summation:9006358] Binding of MECP2 to the promoter of the BDNF gene represses ...
[Complex:R-MMU-9021921] Mecp2:Creb1:Sst gene [nucleoplasm]
[Reaction:R-MMU-9021925] Mecp2:Creb1 binds Sst gene promoter
[Summation:9021920] Based on studies in mice, the complex of MECP2 and CREB1 bin...
[RegulationReference:9642006] Positive gene expression regulation by 'Mecp2:Creb1:Sst gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[BlackBoxEvent:R-MMU-9021933] Sst gene expression
[Summation:9021938] Based on studies in mice, transcription of the SST gene, enc...
[Pathway:R-HSA-9022702] MECP2 regulates transcription of neuronal ligands
[Complex:R-MMU-9022016] Mecp2:Gamt gene [nucleoplasm]
[Reaction:R-MMU-9021974] Mecp2 binds Gamt gene promoter
[Summation:9022020] Based on studies in mice, MECP2 binds the promoter region of...
[RegulationReference:9641594] Positive gene expression regulation by 'Mecp2:Gamt gene [nucleoplasm]' MeCP2, a key contributor to neurological disease, activates and represses transcription
[BlackBoxEvent:R-MMU-9021976] Gamt gene expression is stimulated by Mecp2
[Summation:9022014] Based on studies in mice, transcription of the GAMT gene, en...
[Pathway:R-HSA-9022692] Regulation of MECP2 expression and activity
[Complex:R-MMU-9022118] Mecp2:Rbfox1 gene [nucleoplasm]
[Reaction:R-MMU-9021973] Mecp2 binds Rbfox1 gene promoter
[Summation:9022119] Based on studies in mice, MECP2 binds the promoter region of...
[Complex:R-MMU-9022094] Mecp2:Mef2c gene [nucleoplasm]
[Reaction:R-MMU-9021968] Mecp2 binds Mef2c gene promoter

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