UniProt:Q11203 ST3GAL3

chain
  • chain:1-375
checksum C9B7B61AD580EC2E
comment
  • FUNCTION Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta-1,4-GlcNAc-, NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- and NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. The highest activity is toward Gal-beta-1,3-GlcNAc and the lowest toward Gal-beta-1,3-GalNAc.PATHWAY Protein modification; protein glycosylation.TISSUE SPECIFICITY Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.PTM The soluble form derives from the membrane form by proteolytic processing.SIMILARITY Belongs to the glycosyltransferase 29 family.
crossReference
databaseName UniProt
dbId 64474
description
  • recommendedName: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase ecNumber evidence="2"2.4.99.6/ecNumber alternativeName: Beta-galactoside alpha-2,3-sialyltransferase 3 shortName:Alpha 2,3-ST 3 alternativeName: Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase alternativeName: N-acetyllactosaminide alpha-2,3-sialyltransferase alternativeName: ST3Gal III shortName:ST3GalIII alternativeName: ST3N alternativeName: Sialyltransferase 6
displayName UniProt:Q11203 ST3GAL3
geneName
  • ST3GAL3
  • SIAT6
identifier Q11203
isSequenceChanged false
keyword
  • Alternative splicing
  • Disease variant
  • Disulfide bond
  • Epilepsy
  • Glycoprotein
  • Glycosyltransferase
  • Golgi apparatus
  • Membrane
  • Mental retardation
  • Reference proteome
  • Secreted
  • Signal-anchor
  • Transferase
  • Transmembrane
  • Transmembrane helix
modified [InstanceEdit:11703684] Shorser, Solomon, 2021-05-28
name
  • ST3GAL3
otherIdentifier
  • 0007050600
  • 11724137_a_at
  • 11750100_a_at
  • 11753490_a_at
  • 11753789_a_at
  • 11753790_x_at
  • 1555171_at
  • 1555181_a_at
  • 1555678_at
  • 1555702_3p_a_at
  • 1555702_a_at
  • 1555703_3p_at
  • 1555703_at
  • 16663694
  • 225905_s_at
  • 2333480
  • 2333482
  • 2333483
  • 2333484
  • 2333488
  • 2333489
  • 2333490
  • 2333507
  • 2333513
  • 2333515
  • 2333516
  • 2333524
  • 2333530
  • 2333531
  • 2333536
  • 2333537
  • 2333539
  • 2333541
  • 2333543
  • 2333544
  • 2333551
  • 2333552
  • 2333553
  • 2333554
  • 2333555
  • 2333556
  • 2333559
  • 2333560
  • 2333561
  • 52958_at
  • 6487
  • 7900857
  • A_14_P137034
  • A_23_P200999
  • A_24_P268123
  • A_33_P3405966
  • GE471092
  • GO:0000139
  • GO:0003674
  • GO:0003836
  • GO:0005515
  • GO:0005575
  • GO:0005576
  • GO:0005622
  • GO:0005737
  • GO:0005794
  • GO:0005975
  • GO:0006464
  • GO:0006486
  • GO:0006629
  • GO:0006790
  • GO:0008118
  • GO:0008150
  • GO:0008373
  • GO:0009058
  • GO:0009312
  • GO:0010706
  • GO:0016020
  • GO:0016021
  • GO:0016266
  • GO:0016740
  • GO:0016757
  • GO:0018146
  • GO:0019082
  • GO:0032580
  • GO:0034641
  • GO:0043226
  • GO:0044281
  • GO:0044403
  • GO:0097503
  • HMNXSV003049671
  • HMNXSV003053911
  • Hs.48793.1.S2_3p_at
  • Hs2.48793.3.S1_3p_s_at
  • Hs2.48793.7.S1_3p_s_at
  • Hs2.48793.8.S1_3p_a_at
  • Hs2.48793.9.S1_3p_a_at
  • ILMN_1699472
  • ILMN_2350315
  • PH_hs_0003412
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • SIAT6_HUMAN
  • A9Z1W2
  • D3DPX8
  • Q5T4W9
  • Q5T4X0
  • Q5T4X7
  • Q5T4X8
  • Q5T4X9
  • Q5T4Y0
  • Q5T4Y2
  • Q5T4Y3
  • Q5T4Y4
  • Q86UR6
  • Q86UR7
  • Q86UR8
  • Q86UR9
  • Q86US0
  • Q86US1
  • Q86US2
  • Q8IX41
  • Q8IX42
  • Q8IX43
  • Q8IX44
  • Q8IX45
  • Q8IX46
  • Q8IX47
  • Q8IX48
  • Q8IX49
  • Q8IX50
  • Q8IX51
  • Q8IX52
  • Q8IX53
  • Q8IX54
  • Q8IX55
  • Q8IX56
  • Q8IX57
  • Q8IX58
sequenceLength 375
species [Species:48887] Homo sapiens
url http://purl.uniprot.org/uniprot/Q11203
Cite Us!