Reactome | UniProt:Q9Y2Q9 MRPS28

Schema > ReferenceGeneProduct > Entries

UniProt:Q9Y2Q9 MRPS28 Show undefined attributes

chain	transit peptide:1-71 chain:72-187
checksum	2ED0EA43552B9B54
comment	SUBUNIT Component of the mitochondrial small ribosomal subunit (mt-SSU) (PubMed:30566640). Mature mammalian 55S mitochondrial ribosomes consist of a small (28S) and a large (39S) subunit. The 28S small subunit contains a 12S ribosomal RNA (12S mt-rRNA) and 30 different proteins. The 39S large subunit contains a 16S rRNA (16S mt-rRNA), a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays an integral structural role, and 52 different proteins.SUBCELLULAR LOCATION The disease is caused by variants affecting the gene represented in this entry.SIMILARITY Belongs to the bacterial ribosomal protein bS1 family.
crossReference	[DatabaseIdentifier:10978967] Pharos - Targets:Q9Y2Q9 [DatabaseIdentifier:11075246] OpenTargets:ENSG00000147586 [DatabaseIdentifier:11624015] RefSeq:NP_054737.1 [DatabaseIdentifier:11786812] PDB:3J9M [DatabaseIdentifier:11786814] PDB:6NU2 [DatabaseIdentifier:11786816] PDB:6NU3 [DatabaseIdentifier:11786817] PDB:6RW4 [DatabaseIdentifier:11786819] PDB:6RW5 [DatabaseIdentifier:11786820] PDB:6VLZ [DatabaseIdentifier:11786821] PDB:6VMI [DatabaseIdentifier:11786824] PDB:6ZM5 [DatabaseIdentifier:11786825] PDB:6ZM6 [DatabaseIdentifier:11786826] PDB:6ZS9 [DatabaseIdentifier:11786829] PDB:6ZSA [DatabaseIdentifier:11786830] PDB:6ZSB [DatabaseIdentifier:11786833] PDB:6ZSC [DatabaseIdentifier:11786834] PDB:6ZSD [DatabaseIdentifier:11786836] PDB:6ZSE [DatabaseIdentifier:11786840] PDB:6ZSG [DatabaseIdentifier:11786841] PDB:7A5F [DatabaseIdentifier:11786842] PDB:7A5G [DatabaseIdentifier:11786843] PDB:7A5I [DatabaseIdentifier:11786845] PDB:7A5K [DatabaseIdentifier:11786847] PDB:7L08 [DatabaseIdentifier:11786848] PDB:7OG4 [DatabaseIdentifier:11786851] PDB:7P2E [DatabaseIdentifier:11786853] PDB:7PNX [DatabaseIdentifier:11786854] PDB:7PNY [DatabaseIdentifier:11786855] PDB:7PNZ [DatabaseIdentifier:11786859] PDB:7PO0 [DatabaseIdentifier:11786860] PDB:7PO1 [DatabaseIdentifier:11786862] PDB:7PO2 [DatabaseIdentifier:11786863] PDB:7PO3 [DatabaseIdentifier:11786864] PDB:7QI4 [DatabaseIdentifier:11786868] PDB:7QI5 [DatabaseIdentifier:11786869] PDB:7QI6 [DatabaseIdentifier:11786870] PDB:8ANY [DatabaseIdentifier:11786873] PDB:8CSP [DatabaseIdentifier:11786874] PDB:8CSQ [DatabaseIdentifier:11786876] PDB:8CSR [DatabaseIdentifier:11786878] PDB:8CSS [DatabaseIdentifier:11786880] PDB:8CST [DatabaseIdentifier:11786881] PDB:8CSU [DatabaseIdentifier:11786883] PDB:8OIR [DatabaseIdentifier:11786891] PDB:8OIS [DatabaseIdentifier:11839009] PRO:Q9Y2Q9 [DatabaseIdentifier:11848751] GeneCards:Q9Y2Q9 [DatabaseIdentifier:11902637] HPA:ENSG00000147586-MRPS28 [DatabaseIdentifier:12104046] Ensembl:ENSG00000147586 [DatabaseIdentifier:12104047] Ensembl:ENST00000276585 [DatabaseIdentifier:12104048] Ensembl:ENSP00000276585
databaseName	UniProt
dbId	63816
description	recommendedName: fullName evidence="5"Small ribosomal subunit protein bS1m alternativeName: 28S ribosomal protein S28, mitochondrial shortName: MRP-S28 shortName: S28mt alternativeName: 28S ribosomal protein S35, mitochondrial shortName: MRP-S35 shortName: S35mt
displayName	UniProt:Q9Y2Q9 MRPS28
geneName	MRPS28 MRPS35 HSPC007
identifier	Q9Y2Q9
isSequenceChanged	false
keyword	3D-structure Acetylation Disease variant Mitochondrion Phosphoprotein Primary mitochondrial disease Reference proteome Ribonucleoprotein Ribosomal protein Transit peptide
modified	[InstanceEdit:12187927] Wright, Adam, 2024-03-12
name	MRPS28
otherIdentifier	11730249_at 11747847_s_at 17078480 219819_PM_s_at 219819_s_at 28957 3141810 3141811 3141812 3141837 3141838 3141850 53106_at 8151471 A_23_P169050 GE80754 GO:0003723 GO:0005739 GO:0005743 GO:0005763 GO:0005840 GO:0032543 GO:0043226 GO:0140053 GO:1990904 HMNXSV003012351 ILMN_1718424 PH_hs_0003616 PH_hs_0035433 g7661729_3p_a_at
physicalEntity	[EntityWithAccessionedSequence:R-HSA-5368201] MRPS28 [mitochondrial inner membrane] - Homo sapiens
referenceDatabase	[ReferenceDatabase:2] UniProt
referenceGene	[ReferenceDNASequence:8961104] ENSEMBL:ENSG00000147586 MRPS28 [ReferenceDNASequence:11026074] KEGG Gene (Homo sapiens):28957 MRPS28 [ReferenceDNASequence:11275867] NCBI Gene:28957 MRPS28 [ReferenceDNASequence:11275868] BioGPS Gene:28957 MRPS28 [ReferenceDNASequence:11275869] CTD Gene:28957 MRPS28 [ReferenceDNASequence:11275870] dbSNP Gene:28957 MRPS28 [ReferenceDNASequence:11275871] Monarch:28957 MRPS28 [ReferenceDNASequence:11354895] ENSEMBL_homo_sapiens_GENE:ENSG00000147586.10 MRPS28 [ReferenceDNASequence:11516579] UCSC:Q9Y2Q9 MRPS28 [ReferenceDNASequence:11799847] OMIM:611990 MRPS28 [ReferenceDNASequence:11876106] HGNC:14513 MRPS28 [ReferenceDNASequence:12191967] COSMIC (genes):MRPS28 MRPS28
referenceTranscript	[ReferenceRNASequence:11466913] RefSeq:NM_014018.2 MRPS28
schemaClass	ReferenceGeneProduct
secondaryIdentifier	RT28_HUMAN B2RDZ7 Q96Q21
sequenceLength	187
species	[Species:48887] Homo sapiens
url	https://purl.uniprot.org/uniprot/Q9Y2Q9

Referrals

(referenceEntity)

[EntityWithAccessionedSequence:R-HSA-5368201] MRPS28 [mitochondrial inner membrane]

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