UniProt:Q06210 GFPT1

chain
  • initiator methionine:1
  • chain:2-699
checksum F0533A7B762C7B98
comment
  • FUNCTION Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes ARNTL/BMAL1 and CRY1.PATHWAY Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1.SUBUNIT Homotetramer (Probable), may also exist as homodimers.TISSUE SPECIFICITY Isoform 1 is predominantly expressed in skeletal muscle. Not expressed in brain. Seems to be selectively expressed in striated muscle.
crossReference
databaseName UniProt
dbId 55576
description
  • recommendedName: Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 ecNumber evidence="3"2.6.1.16/ecNumber alternativeName: D-fructose-6-phosphate amidotransferase 1 alternativeName: Glutamine:fructose-6-phosphate amidotransferase 1 shortName:GFAT 1 shortName:GFAT1 alternativeName: Hexosephosphate aminotransferase 1
displayName UniProt:Q06210 GFPT1
geneName
  • GFPT1
  • GFAT
  • GFPT
identifier Q06210
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Aminotransferase
  • Biological rhythms
  • Congenital myasthenic syndrome
  • Disease variant
  • Glutamine amidotransferase
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Transferase
modified [InstanceEdit:11703684] Shorser, Solomon, 2021-05-28
name
  • GFPT1
otherIdentifier
  • 0002480373
  • 11720221_at
  • 11720222_at
  • 11720223_at
  • 11757975_s_at
  • 11758456_s_at
  • 16898578
  • 202721_s_at
  • 202722_s_at
  • 226886_at
  • 227027_at
  • 2558063
  • 2558064
  • 2558065
  • 2558066
  • 2558067
  • 2558068
  • 2558069
  • 2558070
  • 2558071
  • 2558072
  • 2558073
  • 2558074
  • 2558075
  • 2558077
  • 2558078
  • 2558082
  • 2558085
  • 2558086
  • 2558087
  • 2558088
  • 2558089
  • 2558092
  • 2558094
  • 2558095
  • 2558097
  • 2558099
  • 2558102
  • 2558109
  • 2558110
  • 2673
  • 32626_at
  • 3284171
  • 61346_at
  • 8052762
  • 90240_at
  • A_23_P345887
  • A_23_P44083
  • A_33_P3243153
  • GE54887
  • GE58132
  • GO:0003674
  • GO:0004360
  • GO:0005575
  • GO:0005576
  • GO:0005615
  • GO:0005622
  • GO:0005737
  • GO:0005829
  • GO:0006002
  • GO:0006047
  • GO:0006048
  • GO:0006091
  • GO:0006112
  • GO:0006464
  • GO:0006487
  • GO:0006520
  • GO:0006541
  • GO:0006950
  • GO:0007165
  • GO:0008150
  • GO:0008483
  • GO:0009058
  • GO:0016740
  • GO:0032922
  • GO:0034641
  • GO:0036498
  • GO:0043226
  • GO:0044281
  • GO:0048511
  • GO:0070062
  • GO:0097367
  • GO:1901135
  • GO:1901137
  • HMNXSV003038583
  • Hs.13396.0.A1_3p_at
  • Hs.1674.0.S1_3p_a_at
  • Hs.24723.0.A1_3p_at
  • ILMN_1696000
  • ILMN_2220184
  • ILMN_2220187
  • M90516_at
  • PH_hs_0000227
  • PH_hs_0039878
  • TC02001948.hg
  • g4503980_3p_a_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • GFPT1_HUMAN
  • Q53QE6
  • Q9BXF8
sequenceLength 699
species [Species:48887] Homo sapiens
url http://purl.uniprot.org/uniprot/Q06210
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