UniProt:P08236 GUSB

chain
  • signal peptide:1-22
  • chain:23-651
checksum 6BA7B1D935C9ABBD
comment
  • FUNCTION Plays an important role in the degradation of dermatan and keratan sulfates.ACTIVITY REGULATION Inhibited by L-aspartic acid.SUBUNIT Homotetramer.PTM N-linked glycosylated with 3 to 4 oligosaccharide chains.SIMILARITY Belongs to the glycosyl hydrolase 2 family.
crossReference
databaseName UniProt
dbId 50814
description
  • recommendedName: Beta-glucuronidase ecNumber3.2.1.31/ecNumber alternativeName: Beta-G1
displayName UniProt:P08236 GUSB
geneName
  • GUSB
identifier P08236
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • Direct protein sequencing
  • Disease variant
  • Glycoprotein
  • Glycosidase
  • Hydrolase
  • Lysosome
  • Mucopolysaccharidosis
  • Reference proteome
  • Signal
modified [InstanceEdit:11703684] Shorser, Solomon, 2021-05-28
name
  • GUSB
otherIdentifier
  • 11719271_s_at
  • 17058176
  • 202605_at
  • 2868809
  • 2946613
  • 2990
  • 3004396
  • 3053693
  • 3053694
  • 3053695
  • 3053696
  • 3053697
  • 3053698
  • 3053699
  • 3053700
  • 3053706
  • 3053707
  • 3053709
  • 3053711
  • 3053713
  • 3053715
  • 3053717
  • 3053722
  • 3053723
  • 3053724
  • 3053725
  • 3053729
  • 33308_at
  • 8139859
  • A_23_P334608
  • GE61184
  • GO:0002376
  • GO:0003674
  • GO:0004553
  • GO:0004566
  • GO:0005102
  • GO:0005575
  • GO:0005576
  • GO:0005615
  • GO:0005622
  • GO:0005737
  • GO:0005764
  • GO:0005773
  • GO:0005975
  • GO:0006027
  • GO:0006810
  • GO:0008150
  • GO:0008152
  • GO:0009056
  • GO:0016020
  • GO:0016192
  • GO:0016787
  • GO:0016798
  • GO:0019391
  • GO:0019904
  • GO:0030214
  • GO:0030246
  • GO:0031410
  • GO:0035578
  • GO:0043202
  • GO:0043226
  • GO:0043231
  • GO:0043312
  • GO:0044281
  • GO:0070062
  • GO:1904813
  • HMNXSV003041271
  • ILMN_1669878
  • M15182_at
  • PH_hs_0023271
  • PH_hs_0032345
  • TC07001457.hg
  • g4504222_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • BGLR_HUMAN
  • B4E1F6
  • E9PCV0
  • Q549U0
  • Q96CL9
sequenceLength 651
species [Species:48887] Homo sapiens
url http://purl.uniprot.org/uniprot/P08236
Cite Us!