UniProt:Q09428 ABCC8

chain
  • chain:1-1581
checksum 09CF2EC97899D1CE
comment
  • FUNCTION Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release.SUBUNIT Interacts with KCNJ11.INTERACTION The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.DISEASE The disease is caused by variants affecting the gene represented in this entry.MISCELLANEOUS Abundant isoform with prodiabetic properties, predominant in heart.SIMILARITY Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.ONLINE INFORMATION Database for mutations in ABC proteins
created [InstanceEdit:400710] Schmidt, EE, 2009-03-25 05:33:35
crossReference
databaseName UniProt
dbId 405344
description
  • recommendedName: ATP-binding cassette sub-family C member 8 alternativeName: Sulfonylurea receptor 1
displayName UniProt:Q09428 ABCC8
geneName
  • ABCC8
  • HRINS
  • SUR
  • SUR1
identifier Q09428
isSequenceChanged false
keyword
  • 3D-structure
  • Alternative splicing
  • ATP-binding
  • Cell membrane
  • Diabetes mellitus
  • Disease variant
  • Glycoprotein
  • Membrane
  • Nucleotide-binding
  • Receptor
  • Reference proteome
  • Repeat
  • Transmembrane
  • Transmembrane helix
  • Transport
modified [InstanceEdit:12187927] Wright, Adam, 2024-03-12
name
  • ABCC8
otherIdentifier
  • 11723976_at
  • 11753931_a_at
  • 11757771_a_at
  • 16736278
  • 210246_PM_s_at
  • 210246_s_at
  • 3364877
  • 3364879
  • 3364880
  • 3364882
  • 3364883
  • 3364888
  • 3364890
  • 3364891
  • 3364894
  • 3364901
  • 3364904
  • 3364907
  • 3364910
  • 3364913
  • 3364914
  • 3364915
  • 3364916
  • 3364917
  • 3364918
  • 3364919
  • 3364920
  • 3364921
  • 3364923
  • 3364927
  • 3364929
  • 3364930
  • 3364933
  • 3364936
  • 3364941
  • 3364946
  • 3364948
  • 3364951
  • 3364952
  • 3364954
  • 3364960
  • 3364964
  • 3364974
  • 3364975
  • 3364980
  • 3364982
  • 3364983
  • 3364987
  • 3364988
  • 3364989
  • 3364992
  • 3364994
  • 3364998
  • 3364999
  • 3365000
  • 41792_at
  • 53384_g_at
  • 6833
  • 7946860
  • A_23_P24774
  • GE57802
  • GO:0000166
  • GO:0001678
  • GO:0003012
  • GO:0003013
  • GO:0003824
  • GO:0005215
  • GO:0005267
  • GO:0005515
  • GO:0005524
  • GO:0005886
  • GO:0006813
  • GO:0007565
  • GO:0007613
  • GO:0008281
  • GO:0008282
  • GO:0008542
  • GO:0009268
  • GO:0009410
  • GO:0010043
  • GO:0010989
  • GO:0015272
  • GO:0016020
  • GO:0016525
  • GO:0016787
  • GO:0016887
  • GO:0019829
  • GO:0022414
  • GO:0023052
  • GO:0030154
  • GO:0030672
  • GO:0031004
  • GO:0031410
  • GO:0032496
  • GO:0032760
  • GO:0032868
  • GO:0032991
  • GO:0034330
  • GO:0035774
  • GO:0042383
  • GO:0042626
  • GO:0043226
  • GO:0043268
  • GO:0043531
  • GO:0044325
  • GO:0044877
  • GO:0046676
  • GO:0048856
  • GO:0048870
  • GO:0050768
  • GO:0050877
  • GO:0050905
  • GO:0055085
  • GO:0060089
  • GO:0060253
  • GO:0061535
  • GO:0061855
  • GO:0071310
  • GO:0071805
  • GO:0098662
  • GO:0140359
  • GO:0140657
  • GO:1900721
  • GO:1905075
  • GO:1905604
  • GO:1990573
  • HMNXSV003039832
  • ILMN_1767129
  • PH_hs_0003567
  • TC11001457.hg
  • U63455_at
  • g3643189_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • ABCC8_HUMAN
  • A6NMX8
  • E3UYX6
  • O75948
  • Q16583
sequenceLength 1581
species [Species:48887] Homo sapiens
url https://purl.uniprot.org/uniprot/Q09428

Referrals

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