hepatic stellate cell

created [InstanceEdit:2473613] Jassal, Bijay, 2012-09-24
databaseName CL
dbId 2473608
definition A cell that is found in the perisinusoidal space of the liver that is capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components that can contribute to liver fibrosis. This activated state has a myofibroblast-like phenotype, though it's not clear in the literature if this is terminally differentiated. This cell type comprises approximately 8-15% of total cells in the liver.
displayName hepatic stellate cell
identifier 0000632
name
  • hepatic stellate cell
referenceDatabase [ReferenceDatabase:2473614] CL
schemaClass CellType
synonym
  • hepatic perisinusoidal cell
  • ito cell
  • perisinusoidal cell
  • HSC
url https://www.ebi.ac.uk/ols4/ontologies/cl/classes?obo_id=CL:0000632
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