The bifunctional enzymes heparan sulfate N-deacetylases/N-su...

created [InstanceEdit:2022912] Jassal, B, 2011-12-01
dbId 2022900
displayName The bifunctional enzymes heparan sulfate N-deacetylases/N-su...
modified [InstanceEdit:2090024] Jassal, B, 2012-02-06
schemaClass Summation
text The bifunctional enzymes heparan sulfate N-deacetylases/N-sulfotransferases 1-4 (NDST1-4) catalyse both the N-deacetylation and the N-sulfation of N-acetylglucosamine (GlcNAc) of heparan (Dixon et al. 1995, Duncan et al. 2006, Aikawa & Esko 1999, Aikawa et al. 2001). Once GlcNAc is deacetylated to glucosamine, the NDST enzymes can sulfate it on position 2 (N).
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