UniProt:Q9NP59 SLC40A1

chain
  • chain:1-571
checksum E4D6B5594C904959
comment
  • FUNCTION May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).SUBUNIT Identified in a complex with STOM.TISSUE SPECIFICITY Detected in erythrocytes (at protein level). Expressed in placenta, intestine, muscle and spleen.SIMILARITY Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
created [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
crossReference
databaseName UniProt
dbId 153505
description
  • recommendedName: Solute carrier family 40 member 1 alternativeName: Ferroportin-1 alternativeName: Iron-regulated transporter 1
displayName UniProt:Q9NP59 SLC40A1
geneName
  • SLC40A1
  • FPN1
  • IREG1
  • SLC11A3
  • MSTP079
identifier Q9NP59
isSequenceChanged false
keyword
  • 3D-structure
  • Cell membrane
  • Disease variant
  • Glycoprotein
  • Ion transport
  • Iron
  • Iron transport
  • Membrane
  • Reference proteome
  • Transmembrane
  • Transmembrane helix
  • Transport
modified [InstanceEdit:11703684] Shorser, Solomon, 2021-05-28
name
  • SLC40A1
otherIdentifier
  • 0003190601
  • 0103360035
  • 11715788_a_at
  • 11715789_a_at
  • 16906419
  • 223044_at
  • 2591858
  • 2591859
  • 2591860
  • 2591861
  • 2591862
  • 2591864
  • 2591865
  • 2591866
  • 2591868
  • 2591874
  • 2591875
  • 2591877
  • 2591878
  • 2591884
  • 2591887
  • 2591888
  • 2591889
  • 2591890
  • 2591891
  • 30061
  • 45826_at
  • 8057677
  • A_23_P102391
  • GE58603
  • GO:0003674
  • GO:0005381
  • GO:0005515
  • GO:0005575
  • GO:0005622
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0005829
  • GO:0005886
  • GO:0005887
  • GO:0006810
  • GO:0006811
  • GO:0006879
  • GO:0008150
  • GO:0015093
  • GO:0016020
  • GO:0016021
  • GO:0016323
  • GO:0017046
  • GO:0022857
  • GO:0034755
  • GO:0042592
  • GO:0043226
  • GO:0055072
  • GO:0055085
  • GO:0060586
  • GO:1903988
  • HMNXSV003009430
  • ILMN_1761833
  • ILMN_2053103
  • PH_hs_0024808
  • TC02002614.hg
  • TC02004748.hg
  • g12053382_3p_at
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • S40A1_HUMAN
  • Q6FI62
  • Q7Z4F8
  • Q8IVB2
  • Q9NRL0
sequenceLength 571
species [Species:48887] Homo sapiens
url http://purl.uniprot.org/uniprot/Q9NP59
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