UniProt:Q99P21 Mutyh

chain
  • chain:1-515
checksum 10DC39CC3A01AE5B
comment
  • FUNCTION Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.TISSUE SPECIFICITY Expressed in heart, lung, liver, intestine, brain and thymus.SIMILARITY Belongs to the Nth/MutY family.
created [InstanceEdit:143527] Schmidt, EE, 2004-11-12 07:45:10
crossReference
databaseName UniProt
dbId 150751
description
  • recommendedName: Adenine DNA glycosylase ecNumber evidence="4"3.2.2.31/ecNumber alternativeName: MutY homolog shortName:mMYH
displayName UniProt:Q99P21 Mutyh
geneName
  • Mutyh
  • Myh
identifier Q99P21
isSequenceChanged false
keyword
  • 4Fe-4S
  • DNA damage
  • DNA repair
  • Glycosidase
  • Hydrolase
  • Iron
  • Iron-sulfur
  • Metal-binding
  • Mitochondrion
  • Nucleus
  • Reference proteome
modified [InstanceEdit:11703684] Shorser, Solomon, 2021-05-28
name
  • Mutyh
otherIdentifier
  • 10507362
  • 1422816_a_at
  • 17417530
  • 4465204
  • 4512356
  • 4536859
  • 4609759
  • 4631547
  • 4671077
  • 4702908
  • 4726878
  • 4775190
  • 5000404
  • 5133482
  • 5143839
  • 5154818
  • 5223615
  • 5273432
  • 5289836
  • 5318858
  • 5446406
  • 5500161
  • 70603
  • 96558_at
  • A_52_P165831
  • A_55_P1978122
  • GE126837
  • GO:0000701
  • GO:0003674
  • GO:0003677
  • GO:0003824
  • GO:0005575
  • GO:0005622
  • GO:0005634
  • GO:0005654
  • GO:0005737
  • GO:0005739
  • GO:0006259
  • GO:0006281
  • GO:0006284
  • GO:0006298
  • GO:0006950
  • GO:0006974
  • GO:0006979
  • GO:0008150
  • GO:0008152
  • GO:0008219
  • GO:0016787
  • GO:0016798
  • GO:0019104
  • GO:0032357
  • GO:0032407
  • GO:0034039
  • GO:0034641
  • GO:0035485
  • GO:0043167
  • GO:0043226
  • GO:0046872
  • GO:0051536
  • GO:0051539
  • GO:0060546
  • ILMN_1219741
  • ILMN_2590061
  • ILMN_2920924
  • aa409965_at
  • mMC004866
physicalEntity
referenceDatabase [ReferenceDatabase:2] UniProt
referenceGene
referenceTranscript
schemaClass ReferenceGeneProduct
secondaryIdentifier
  • MUTYH_MOUSE
  • A2AGE3
sequenceLength 515
species [Species:48892] Mus musculus
url http://purl.uniprot.org/uniprot/Q99P21
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