created | [InstanceEdit:1504208] Rothfels, K, 2011-08-23 |
dbId | 1504206 |
displayName | The PDZ domain of mDvl1 mediates a direct interaction with a... |
schemaClass | Summation |
text | The PDZ domain of mDvl1 mediates a direct interaction with a conserved motif of FZD7 that is located just after the seventh transmembrane segment of the receptor. This FZD-Dvl interaction is thought to initiate recruitment of Axin-GSK3-beta to the membrane by virtue of the interaction between Axin and the DIX domain of Dvl. |
(summation) |
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