Reactome | FURIN translocates to the plasma membrane

Schema > BlackBoxEvent > Entries

category	omitted
compartment	[Compartment:20699] Golgi membrane [Compartment:876] plasma membrane
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10813918
displayName	FURIN translocates to the plasma membrane
eventOf	[Pathway:R-CEL-2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9736953] FURIN translocates to the plasma membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-CEL-157049] FURIN [Golgi membrane]
isInDisease	false
isInferred	true
name	FURIN translocates to the plasma membrane
output	[EntityWithAccessionedSequence:R-CEL-2159856] FURIN [plasma membrane]
releaseDate	2024-03-27
schemaClass	BlackBoxEvent
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9736953
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-2173796] SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
(inferredTo)	[BlackBoxEvent:R-HSA-9736953] FURIN translocates to the plasma membrane