Reactome | daf-18 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-CEL-6807206] USP13 and OTUD3 deubiquitinate PTEN - Caenorhabditis elegans
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10803007
displayName	daf-18 [cytosol]
endCoordinate	403
hasModifiedResidue	[GroupModifiedResidue:10803005] ubiquitinylated lysine (K48polyUb [cytosol]) at 289 (in Homo sapiens)
inDisease	false
inferredFrom	[DefinedSet:R-HSA-8948784] PolyUb-PTEN,K48polyUb-K289-PTEN [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-8948777] K48polyUb-K289-PTEN [cytosol] - Homo sapiens
memberOf	[DefinedSet:R-CEL-8948842] PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] - Caenorhabditis elegans
name	daf-18 K48polyUb-K289-PTEN G5EE01
producedByEvent	[Reaction:R-CEL-8948775] MKRN1 polyubiquitinates PTEN - Caenorhabditis elegans
referenceEntity	[ReferenceGeneProduct:10753266] UniProt:G5EE01
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-8948777
startCoordinate	2

(hasMember)	[DefinedSet:R-CEL-8948842] PolyUb-PTEN, K48polyUb-K289-PTEN, PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol]
(output)	[Reaction:R-CEL-8948775] MKRN1 polyubiquitinates PTEN
(input)	[Reaction:R-CEL-6807206] USP13 and OTUD3 deubiquitinate PTEN
(inferredTo)	[DefinedSet:R-HSA-8948784] PolyUb-PTEN,K48polyUb-K289-PTEN [cytosol] [EntityWithAccessionedSequence:R-HSA-8948777] K48polyUb-K289-PTEN [cytosol]

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