Reactome | EPHB:NMDAR binds TIAM1

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EPHB:NMDAR binds TIAM1 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10786967
displayName	EPHB:NMDAR binds TIAM1
eventOf	[Pathway:R-CEL-3928662] EPHB-mediated forward signaling - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-3928627] EPHB phosphorylates TIAM1 - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-3928645] EPHB:NMDAR binds TIAM1 - Homo sapiens
input	[Complex:R-CEL-3928531] EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly [plasma membrane] [EntityWithAccessionedSequence:R-CEL-195013] tiam-1 [cytosol]
isInDisease	false
isInferred	true
name	EPHB:NMDAR binds TIAM1
output	[Complex:R-CEL-3928541] EFNBs:p-EPHBs:SFKs:Glu:p-NMDAR:Gly:TIAM1 [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-3928645
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-3928662] EPHB-mediated forward signaling
(precedingEvent)	[Reaction:R-CEL-3928627] EPHB phosphorylates TIAM1
(inferredTo)	[Reaction:R-HSA-3928645] EPHB:NMDAR binds TIAM1

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