Reactome | SLC25A1 exchanges CIT and MAL

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SLC25A1 exchanges CIT and MAL Show undefined attributes

catalystActivity	[CatalystActivity:10745834] tricarboxylic acid transmembrane transporter activity of SLC25A1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
dbId	10745836
displayName	SLC25A1 exchanges CIT and MAL
eventOf	[Pathway:R-CEL-428643] Organic anion transporters - Caenorhabditis elegans
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-75848] ACLY tetramer transforms CIT to Ac-CoA - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-75849] SLC25A1 exchanges CIT and MAL - Homo sapiens
input	[SimpleEntity:R-ALL-29654] CIT [mitochondrial matrix] [SimpleEntity:R-ALL-198498] MAL [cytosol]
isInDisease	false
isInferred	true
name	SLC25A1 exchanges CIT and MAL SLC25A1 exports citrate from mitochondrion in exchange for malate Transport of Citrate from Mitochondrial Matrix to cytosol
output	[SimpleEntity:R-ALL-76190] CIT [cytosol] [SimpleEntity:R-ALL-113544] MAL [mitochondrial matrix]
precedingEvent	[Reaction:R-CEL-70975] CS acetylates OA to citrate - Caenorhabditis elegans
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-75849
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-CEL-75848] ACLY tetramer transforms CIT to Ac-CoA
(hasEvent)	[Pathway:R-CEL-428643] Organic anion transporters
(inferredTo)	[Reaction:R-HSA-75849] SLC25A1 exchanges CIT and MAL

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