Reactome | IKK complex recruitment mediated by RIP1

Schema > Pathway > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10652417
displayName	IKK complex recruitment mediated by RIP1
eventOf	[Pathway:R-GGA-937061] TRIF (TICAM1)-mediated TLR4 signaling - Gallus gallus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-GGA-168921] TRIF:activated TLR3/TLR4 complex recruits RIP1 - Gallus gallus [Reaction:R-GGA-168915] K63-linked ubiquitination of RIP1 bound to the activated TLR complex - Gallus gallus
inferredFrom	[Pathway:R-HSA-937041] IKK complex recruitment mediated by RIP1 - Homo sapiens
isInDisease	false
isInferred	true
name	IKK complex recruitment mediated by RIP1
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:49591] Gallus gallus
stId	R-GGA-937041
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-GGA-937061] TRIF (TICAM1)-mediated TLR4 signaling
(inferredTo)	[Pathway:R-HSA-937041] IKK complex recruitment mediated by RIP1