Reactome | TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane]

Schema > Complex > Entries

TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:10650567] protein serine/threonine kinase activity of TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-GGA-9817397] TBK1, IKBKE phosphorylate RIPK1 at T189 - Gallus gallus
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10650561
displayName	TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane]
hasComponent	[CandidateSet:R-GGA-5357900] BIRC2,3,4 [cytosol] [Complex:R-GGA-9796690] CYLD:SPATA2:LUBAC [cytosol] [GenomeEncodedEntity:R-GGA-3371401] Ghost homologue of TNF-? trimer:TNF-R1 trimer [plasma membrane] [EntityWithAccessionedSequence:R-GGA-9793681] K63,M1polyUb-RIPK1 [cytosol] [DefinedSet:R-GGA-9730454] p-S-TBK1:p-S-TBK1, p-S-IKBKE:p-S-IKBKE [cytosol] 3 × [EntityWithAccessionedSequence:R-GGA-66376] TRADD [cytosol] 3 × [EntityWithAccessionedSequence:R-GGA-66370] TRAF2 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane] - Homo sapiens
name	TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-9817409
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(input)	[Reaction:R-GGA-9817397] TBK1, IKBKE phosphorylate RIPK1 at T189
(physicalEntity)	[CatalystActivity:10650567] protein serine/threonine kinase activity of TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane]
(inferredTo)	[Complex:R-HSA-9817409] TNF-alpha:TNFR1:TRADD:K63,M1polyUb-RIPK1:BIRC2,3,4:LUBAC:SPATA2:CYLD:TBK1,IKBKE [plasma membrane]

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