Reactome | Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]

Schema > Complex > Entries

compartment	[Compartment:12045] endoplasmic reticulum membrane
consumedByEvent	[Reaction:R-GGA-8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol - Gallus gallus
created	[InstanceEdit:10560457] Wright, Adam, 2024-03-07
dbId	10637244
displayName	Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]
hasComponent	[Complex:R-GGA-8866531] ERAD complex [endoplasmic reticulum membrane] [Complex:R-GGA-8866534] Ub-misfolded nascent CFTR [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-8866535] Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] - Homo sapiens
name	Ub-misfolded nascent CFTR:ERAD complex
producedByEvent	[Reaction:R-GGA-8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-8866535
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-8866542] VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol
(output)	[Reaction:R-GGA-8866546] RNF5 and RNF185 ubiquitinate misfolded CFTR
(inferredTo)	[Complex:R-HSA-8866535] Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane]

Cite Us!