Reactome | RPS6KA1-dependent phosphorylation of MITF-M

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RPS6KA1-dependent phosphorylation of MITF-M Show undefined attributes

catalystActivity	[CatalystActivity:10556186] protein serine/threonine kinase activity of p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10556188
displayName	RPS6KA1-dependent phosphorylation of MITF-M
eventOf	[Pathway:R-XTR-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9824994] RPS6KA1-dependent phosphorylation of MITF-M - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-9824664] mitf [nucleoplasm]
isInDisease	false
isInferred	true
name	RPS6KA1-dependent phosphorylation of MITF-M
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-XTR-9824967] phospho-mitf [nucleoplasm]
regulatedBy	[PositiveRegulation:10556179] Positive regulation by 'p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-9824994
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-9856649] Transcriptional and post-translational regulation of MITF-M expression and activity
(inferredTo)	[Reaction:R-HSA-9824994] RPS6KA1-dependent phosphorylation of MITF-M