Reactome | L1 binds to AP-2 Clathrin complex

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10505295
displayName	L1 binds to AP-2 Clathrin complex
eventOf	[Pathway:R-XTR-437239] Recycling pathway of L1 - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-392749] Transport of L1 into endosomes - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-392748] L1 binds to AP-2 Clathrin complex - Homo sapiens
input	[Complex:R-XTR-177505] Clathrin:AP-2 complex [plasma membrane] [EntityWithAccessionedSequence:R-XTR-191465] ncam2 [plasma membrane]
isInDisease	false
isInferred	true
name	L1 binds to AP-2 Clathrin complex
output	[Complex:R-XTR-555064] L1:clathrin-coated vesicle [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-392748
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-437239] Recycling pathway of L1
(precedingEvent)	[Reaction:R-XTR-392749] Transport of L1 into endosomes
(inferredTo)	[Reaction:R-HSA-392748] L1 binds to AP-2 Clathrin complex