Reactome | CD28 homodimer binds B7-1 homodimer

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10486564] Wright, Adam, 2024-03-07
dbId	10504841
displayName	CD28 homodimer binds B7-1 homodimer
eventOf	[Pathway:R-XTR-389356] CD28 co-stimulation - Xenopus tropicalis
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-XTR-388831] Phosphorylation of CD28 - Xenopus tropicalis
inferredFrom	[Reaction:R-HSA-388811] CD28 homodimer binds B7-1 homodimer - Homo sapiens
input	[Complex:R-XTR-179780] CD28 homodimer [plasma membrane] [Complex:R-XTR-179787] CD80 dimer [plasma membrane]
isInDisease	false
isInferred	true
name	CD28 homodimer binds B7-1 homodimer
output	[Complex:R-XTR-388767] CD28:B7-1 [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-388811
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-XTR-389356] CD28 co-stimulation
(precedingEvent)	[Reaction:R-XTR-388831] Phosphorylation of CD28
(inferredTo)	[Reaction:R-HSA-388811] CD28 homodimer binds B7-1 homodimer