Reactome | NEIL1:AP-dsDNA [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10464381] DNA-(apurinic or apyrimidinic site) endonuclease activity of NEIL1,NEIL2:AP-dsDNA [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-DRE-5649711] NEIL1,NEIL2 incises DNA strand 5' to the AP site - Danio rerio
created	[InstanceEdit:10427439] Wright, Adam, 2024-03-07
dbId	10464332
displayName	NEIL1:AP-dsDNA [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-DRE-110187] Ghost homologue of AP-dsDNA [nucleoplasm] [EntityWithAccessionedSequence:R-DRE-5649648] NEIL1 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-5649693] NEIL1,NEIL2:AP-dsDNA [nucleoplasm] - Homo sapiens [Complex:R-HSA-5649669] NEIL1:AP-dsDNA [nucleoplasm] - Homo sapiens
name	NEIL1:AP-dsDNA
producedByEvent	[Reaction:R-DRE-5649673] NEIL1 cleaves FapyA from damaged DNA - Danio rerio [Reaction:R-DRE-5649664] NEIL1 cleaves FapyG from damaged DNA - Danio rerio [Reaction:R-DRE-9629149] NEIL1 cleaves thymine glycol from damaged DNA - Danio rerio [Reaction:R-DRE-5649658] NEIL1 cleaves DHU from damaged DNA - Danio rerio
schemaClass	Complex
species	[Species:68323] Danio rerio
stId	R-DRE-5649669
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-DRE-5649711] NEIL1,NEIL2 incises DNA strand 5' to the AP site
(physicalEntity)	[CatalystActivity:10464381] DNA-(apurinic or apyrimidinic site) endonuclease activity of NEIL1,NEIL2:AP-dsDNA [nucleoplasm]
(inferredTo)	[Complex:R-HSA-5649693] NEIL1,NEIL2:AP-dsDNA [nucleoplasm] [Complex:R-HSA-5649669] NEIL1:AP-dsDNA [nucleoplasm]
(output)	[Reaction:R-DRE-5649673] NEIL1 cleaves FapyA from damaged DNA [Reaction:R-DRE-5649664] NEIL1 cleaves FapyG from damaged DNA [Reaction:R-DRE-9629149] NEIL1 cleaves thymine glycol from damaged DNA [Reaction:R-DRE-5649658] NEIL1 cleaves DHU from damaged DNA