Reactome | VDAC1 transports PYR from cytosol to mitochondrial intermembrane space

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VDAC1 transports PYR from cytosol to mitochondrial intermembrane space Show undefined attributes

catalystActivity	[CatalystActivity:10415091] voltage-gated anion channel activity of VDAC1 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:17927] mitochondrial intermembrane space [Compartment:17906] mitochondrial outer membrane
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10415093
displayName	VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
eventOf	[Pathway:R-SSC-70268] Pyruvate metabolism - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9012374] VDAC1 transports PYR from cytosol to mitochondrial intermembrane space - Homo sapiens
input	[SimpleEntity:R-ALL-29398] PYR [cytosol]
isInDisease	false
isInferred	true
name	VDAC1 transports PYR from cytosol to mitochondrial intermembrane space
output	[SimpleEntity:R-ALL-9012375] PYR [mitochondrial intermembrane space]
precedingEvent	[Reaction:R-SSC-70510] LDH tetramer oxidises LACT to PYR - Sus scrofa [Reaction:R-SSC-9012036] ME1 tetramer decarboxylates MAL to PYR - Sus scrofa [Reaction:R-SSC-71670] PKM dephosphorylates PEP to PYR - Sus scrofa
regulatedBy	[NegativeRegulation:9967071] Negative regulation by 'NO [cytosol]'
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-9012374
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-70268] Pyruvate metabolism
(inferredTo)	[Reaction:R-HSA-9012374] VDAC1 transports PYR from cytosol to mitochondrial intermembrane space

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