Reactome | HHIP binds Hedgehog

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10348221
displayName	HHIP binds Hedgehog
eventOf	[Pathway:R-SSC-5632681] Ligand-receptor interactions - Sus scrofa
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-445448] HHIP binds Hedgehog - Homo sapiens
input	[CandidateSet:R-SSC-5362783] Hh-Npp [extracellular region] [EntityWithAccessionedSequence:R-SSC-445449] HHIP [ciliary membrane]
isInDisease	false
isInferred	true
name	HHIP binds Hedgehog
output	[Complex:R-SSC-445447] Hh-Npp:HHIP [ciliary membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-445448
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-5632681] Ligand-receptor interactions
(inferredTo)	[Reaction:R-HSA-445448] HHIP binds Hedgehog