Reactome | EIF4E [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-SSC-113818] Mature Intronless Transcript Derived mRNA:eIF4E Complex [cytosol] - Sus scrofa [Complex:R-SSC-429989] Partially Deadenylated mRNA Complex [cytosol] - Sus scrofa [Complex:R-SSC-429977] Translatable mRNA Complex [cytosol] - Sus scrofa
consumedByEvent	[Reaction:R-SSC-158447] Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC - Sus scrofa [Reaction:R-SSC-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex - Sus scrofa [Reaction:R-SSC-158484] Release of the SLBP independent Histone mRNA from the NPC - Sus scrofa
created	[InstanceEdit:10314670] Wright, Adam, 2024-03-07
dbId	10318289
displayName	EIF4E [cytosol]
endCoordinate	217
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-72578] EIF4E [cytosol] - Homo sapiens
memberOf	[DefinedSet:R-SSC-1678829] EIF4E1/EIF4E3 [cytosol] - Sus scrofa
name	EIF4E A0A5G2RC36
producedByEvent	[Reaction:R-SSC-72622] Release of eIF4E from the inactive eIF4E:4E-BP complex - Sus scrofa [Reaction:R-SSC-165708] Dissociation of phosphorylated 4EBP1 from eIF4E - Sus scrofa [Reaction:R-SSC-429992] PARN deadenylates mRNA - Sus scrofa [Reaction:R-SSC-429955] CCR4-NOT complex deadenylates mRNA - Sus scrofa
referenceEntity	[ReferenceGeneProduct:10318287] UniProt:A0A5G2RC36
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:49633] Sus scrofa
stId	R-SSC-72578
startCoordinate	2

(output)	[Reaction:R-SSC-429992] PARN deadenylates mRNA [Reaction:R-SSC-429955] CCR4-NOT complex deadenylates mRNA [Reaction:R-SSC-72622] Release of eIF4E from the inactive eIF4E:4E-BP complex [Reaction:R-SSC-165708] Dissociation of phosphorylated 4EBP1 from eIF4E
(hasComponent)	[Complex:R-SSC-429989] Partially Deadenylated mRNA Complex [cytosol] [Complex:R-SSC-429977] Translatable mRNA Complex [cytosol] [Complex:R-SSC-113818] Mature Intronless Transcript Derived mRNA:eIF4E Complex [cytosol] [Complex:R-SSC-141614] Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex [cytosol] [Complex:R-SSC-158501] Mature SLBP independent Histone mRNA:eIF4E complex [cytosol] [Complex:R-SSC-72587] eIF4F [cytosol] [Complex:R-SSC-72581] eIF4E:4E-BP [cytosol] [Complex:R-SSC-165697] eIF4E:4E-BP1-P [cytosol]
(input)	[Reaction:R-SSC-158447] Release of the Mature intronless derived mRNA, TAP, and Aly/Ref from the NPC [Reaction:R-SSC-159050] Release of the Mature intronless transcript derived Histone mRNA:SLBP:eIF4E Complex [Reaction:R-SSC-158484] Release of the SLBP independent Histone mRNA from the NPC
(hasMember)	[DefinedSet:R-SSC-1678829] EIF4E1/EIF4E3 [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-72578] EIF4E [cytosol]

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