Reactome | TRAF1 is cleaved by caspases

Schema > BlackBoxEvent > Entries

catalystActivity	[CatalystActivity:10212795] cysteine-type endopeptidase activity of active caspase-8 [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10274271
displayName	TRAF1 is cleaved by caspases
eventOf	[Pathway:R-BTA-5357905] Regulation of TNFR1 signaling - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-5634228] TRAF1 is cleaved by caspases - Homo sapiens
input	[EntityWithAccessionedSequence:R-BTA-5634163] TRAF1 [cytosol]
isInDisease	false
isInferred	true
name	TRAF1 is cleaved by caspases
output	[EntityWithAccessionedSequence:R-BTA-5634199] TRAF1 [cytosol] [EntityWithAccessionedSequence:R-BTA-5634204] TRAF1 [cytosol]
releaseDate	2024-03-27
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-5634228
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-5357905] Regulation of TNFR1 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-5634228] TRAF1 is cleaved by caspases