Reactome | Engulfed CpG DNA binds to endosomal full-length TLR9

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Engulfed CpG DNA binds to endosomal full-length TLR9 Show undefined attributes

category	binding
compartment	[Compartment:74700] endosome membrane
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10252738
displayName	Engulfed CpG DNA binds to endosomal full-length TLR9
eventOf	[Pathway:R-BTA-168138] Toll Like Receptor 9 (TLR9) Cascade - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1679589] Engulfed CpG DNA binds to endosomal full-length TLR9 - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-BTA-187882] TLR9 [endosome membrane] [OtherEntity:R-ALL-167913] Unmethylated CpG DNA [endosome membrane]
isInDisease	false
isInferred	true
name	Engulfed CpG DNA binds to endosomal full-length TLR9
output	[Complex:R-BTA-187884] fl-TLR9:unmethylated CpG DNA [endosome membrane]
precedingEvent	[Reaction:R-BTA-1678981] TLR9 processing at neutral pH - Bos taurus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-1679589
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-168138] Toll Like Receptor 9 (TLR9) Cascade
(inferredTo)	[Reaction:R-HSA-1679589] Engulfed CpG DNA binds to endosomal full-length TLR9

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