Reactome | IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10299189] transmembrane receptor protein tyrosine kinase activity of IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor - Bos taurus [BlackBoxEvent:R-BTA-8950537] JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated - Bos taurus
created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10237255
displayName	IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]
hasComponent	[Complex:R-BTA-448442] IL27:EBI3 [extracellular region] [Complex:R-BTA-8950163] IL27RA:JAK1 [plasma membrane] [Complex:R-BTA-1067690] IL6ST:JAK1, JAK2, (TYK2) [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-448431] IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane] - Homo sapiens
name	IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2)
producedByEvent	[Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-448431
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor
(input)	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor [BlackBoxEvent:R-BTA-8950537] JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated
(physicalEntity)	[CatalystActivity:10299189] transmembrane receptor protein tyrosine kinase activity of IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]
(inferredTo)	[Complex:R-HSA-448431] IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]