Reactome | Cleavage of collagen VII NC2 region by BMP1

Schema > Reaction > Entries

Cleavage of collagen VII NC2 region by BMP1 Show undefined attributes

catalystActivity	[CatalystActivity:10043208] serine-type endopeptidase activity of Collagen type VII NC2 proteinases [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	10043210
displayName	Cleavage of collagen VII NC2 region by BMP1
eventOf	[Pathway:R-RNO-2214320] Anchoring fibril formation - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Polymerisation:R-RNO-2213195] Formation of anchoring fibrils - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2214330] Cleavage of collagen VII NC2 region by BMP1 - Homo sapiens
input	[Complex:R-RNO-2127449] Collagen type VII hexamer [extracellular region]
isInDisease	false
isInferred	true
name	Cleavage of collagen VII NC2 region by BMP1
output	6 × [EntityWithAccessionedSequence:R-RNO-3605709] Col7a1 [extracellular region] [Complex:R-RNO-2214316] Collagen type VII -NC2 hexamer [extracellular region]
precedingEvent	[Reaction:R-RNO-2214324] Collagen type VII dimerization - Rattus norvegicus
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2214330
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2214320] Anchoring fibril formation
(precedingEvent)	[Polymerisation:R-RNO-2213195] Formation of anchoring fibrils
(inferredTo)	[Reaction:R-HSA-2214330] Cleavage of collagen VII NC2 region by BMP1