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Results (30 results from a total of 518)

partially digested Ag

Identifier: R-ALL-1236713
Compartment: phagolysosome

partially digested Ag

Identifier: R-ALL-1236718
Compartment: cytosol

K48polyUb-partially digested Ag

Identifier: R-ALL-1236918
Compartment: cytosol

DAG is metabolized by DAGL to 2-AG

Identifier: R-HSA-426032
Species: Homo sapiens
Compartment: plasma membrane
Diacylglycerol lipase (DAGL) hydrolyzes diacylglycerol (DAG) at the sn-1 position, producing 2-monoacylglycerols, including 2-arachidonlyglycerol (2-AG) and free fatty acid. This reaction was first characterised for the release of arachidonate from membrane phospholipids in platelets, but is also involved in the spatial and temporal regulation of endocannabinoid signaling in the brain. DAGL exhibits strong selectivity for diacylglycerols over phospholipids, monoacylglycerols, triacylglycerols and fatty acid amides, and prefers the acyl group at sn-1 position to that at sn-2.

Ag-substrate:E3:E2:Ub

Identifier: R-HSA-983126
Species: Homo sapiens
Compartment: cytosol

2-AG hydrolysis to arachidonate by MAGL

Identifier: R-HSA-426043
Species: Homo sapiens
Compartment: cytosol, plasma membrane
Monoacylglycerol lipase (MAGL) is a key enzyme in the hydrolysis of the endocannabinoid 2-arachidonoylglycerol to arachidonate and glycerol. In adipocytes MAGL and hormone-sensitive lipase (LIPE) hydrolyze intracellular triglyceride stores. MAGL may also complement lipoprotein lipase (LPL) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides.

Ag-substrate:E3:E2:Ub

Identifier: R-CFA-983126
Species: Canis familiaris
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-CEL-983126
Species: Caenorhabditis elegans
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-MMU-983126
Species: Mus musculus
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-GGA-983126
Species: Gallus gallus
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-DDI-983126
Species: Dictyostelium discoideum
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-XTR-983126
Species: Xenopus tropicalis
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-BTA-983126
Species: Bos taurus
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-DRE-983126
Species: Danio rerio
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-RNO-983126
Species: Rattus norvegicus
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-SSC-983126
Species: Sus scrofa
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-DME-983126
Species: Drosophila melanogaster
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Ag-substrate:E3:E2:Ub

Identifier: R-PFA-983126
Species: Plasmodium falciparum
Compartment: cytosol
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Exogenous Particulate antigen (Ag)

Identifier: R-ALL-1236716
Compartment: phagolysosome

Exogenous Particulate antigen (Ag)

Identifier: R-ALL-1236714
Compartment: phagocytic vesicle

Exogenous Particulate antigen (Ag)

Identifier: R-ALL-1236726
Compartment: extracellular region

DAG is metabolized by DAGL to 2-AG

Identifier: R-MMU-426032
Species: Mus musculus
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-RNO-426032
Species: Rattus norvegicus
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-CFA-426032
Species: Canis familiaris
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-BTA-426032
Species: Bos taurus
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-SSC-426032
Species: Sus scrofa
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-DRE-426032
Species: Danio rerio
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-XTR-426032
Species: Xenopus tropicalis
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-GGA-426032
Species: Gallus gallus
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

DAG is metabolized by DAGL to 2-AG

Identifier: R-DME-426032
Species: Drosophila melanogaster
Compartment: plasma membrane
This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

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