Search results for UniProt:P55085

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Identifier: R-HSA-389418
Species: Homo sapiens
Compartment: plasma membrane
Primary external reference: UniProt: F2RL1: UniProt:P55085
This is the inactive form of the receptor, before protease activation. Proteinase (protease) activated receptors are activated by the cleavage of an N-terminal extracellular segment by serine proteases, particularly thrombin which activates PAR1, 3 and 4. The cleaved fragment is an activating ligand for the receptor; synthetic peptide mimics of the N-terminal fragment can activate uncleaved receptors.
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