Osvaldo Contreras

Victor Chang Cardiac Research Institute
Reviewed Pathways (3/3)
Date Identifier Pathway Reference
2022-05-02 R-HSA-2173793 Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer BibTex
2022-05-02 R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity BibTex
2022-05-02 R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription BibTex
Reviewed Reactions (15/54)
Date Identifier Reaction Reference
2022-05-02 R-HSA-173488 The SMAD2/3:SMAD4 complex transfers to the nucleus BibTex
2022-05-02 R-HSA-170847 Phosphorylated SMAD2 and SMAD3 form a complex with SMAD4 BibTex
2022-05-02 R-HSA-870437 USP9X (FAM) deubiquitinates SMAD4 BibTex
2022-05-02 R-HSA-870479 USP9X (FAM) binds to ubiquitinated SMAD4 BibTex
2022-05-02 R-HSA-870477 Ubiquitinated SMAD4 translocates from the nucleus to the cytosol BibTex
2022-05-02 R-HSA-870449 TRIM33 monoubiquitinates SMAD4 BibTex
2022-05-02 R-HSA-870538 TRIM33 (Ectodermin) binds SMAD heterotrimer in the nucleus BibTex
2022-05-02 R-HSA-2186747 Ubiquitination of SKI/SKIL by RNF111/SMURF2 BibTex
2022-05-02 R-HSA-2186741 SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL BibTex
2022-05-02 R-HSA-173481 SKI/SKIL binds SMAD complex, suppressing TGF-beta signaling BibTex
2022-05-02 R-NUL-2186736 Rnf111 binds SKI/SKIL in complex with SMAD2/3:SMAD4 upon TGF-beta stimulation BibTex
2022-05-02 R-HSA-2179276 SMURF2 monoubiquitinates SMAD3 BibTex
2022-05-02 R-HSA-2179274 SMURF2 binds SMAD3 phosphorylated in the linker region BibTex
2022-05-02 R-HSA-2176475 Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 BibTex
2022-05-02 R-HSA-2186785 RNF111 ubiquitinates SMAD7 BibTex
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