Antonio Cuadrado

 ORCID
https://orcid.org/0000-0002-4039-7140
Affiliation
Autonomous University of Madrid, Spain, Chair of COST Action CA20121 on ?Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases (BenBedPhar)? Department of Biochemistry Faculty of Medicine
Reviewed Pathways (4/4)
Date Identifier Pathway Reference
2022-02-23 R-HSA-9755511 KEAP1-NFE2L2 pathway BibTex
2022-02-23 R-HSA-9759194 Nuclear events mediated by NFE2L2 BibTex
2022-02-23 R-HSA-9762114 GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 BibTex
2022-02-23 R-HSA-8951664 Neddylation BibTex
Reviewed Reactions (73/73)
Date Identifier Reaction Reference
2022-02-23 R-HSA-9707645 HMOX1 gene produces HMOX1 dimer BibTex
2022-02-23 R-HSA-9759189 NFE2L2-dependent PRDX1 gene expression BibTex
2022-02-23 R-HSA-9759129 NFE2L2 binds the PRDX1 promoter BibTex
2022-02-23 R-HSA-8932309 NFE2L2 translocates from cytosol to nucleoplasm BibTex
2022-02-23 R-HSA-8932284 PKC phosphorylates NFE2L2 BibTex
2022-02-23 R-HSA-9762100 MYC- and NICD1-dependent NFE2L2 gene expression BibTex
2022-02-23 R-HSA-9762102 NICD1 binds the NFE2L2 promoter BibTex
2022-02-23 R-HSA-9762097 MYC binds the NFE2L2 promoter BibTex
2022-02-23 R-HSA-8932322 CK2 phosphorylates NFE2L2 BibTex
2022-02-23 R-HSA-9760094 SRXN1 reduces hyperoxidized PRDX1 dimer BibTex
2022-02-23 R-HSA-9759358 NFE2L2-dependent SRXN1 gene expression BibTex
2022-02-23 R-HSA-9759334 NFE2L2 binds the SRXN1 gene BibTex
2022-02-23 R-HSA-9761854 NFE2L2-dependent ME1 gene expression BibTex
2022-02-23 R-HSA-9761825 NFE2L2 binds the ME1 gene BibTex
2022-02-23 R-HSA-9760081 CREBBP, EP300 acetylates NFE2L2 BibTex
2022-02-23 R-HSA-9760082 NFE2L2 binds CREBBP,EP300 BibTex
2022-02-23 R-HSA-9766677 MAP1LC3B binds KEAP1 and SQSTM1 BibTex
2022-02-23 R-HSA-9766645 CUL3:RBX1 ubiquitinates KEAP1 BibTex
2022-02-23 R-HSA-9766687 SESN1,SESN1 bind SQSTM1 and KEAP1 BibTex
2022-02-23 R-HSA-9759172 KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer BibTex
2022-02-23 R-HSA-9759169 p-S349 SQSTM1 oligomer binds KEAP1:CUL3:RBX1 BibTex
2022-02-23 R-HSA-9766532 SQSTM1 oligomer is phosphorylated BibTex
2022-02-23 R-HSA-9759158 SQSTM1 oligomerizes BibTex
2022-02-23 R-HSA-9759157 NFE2L2-dependent SQSTM1 gene expression BibTex
2022-02-23 R-HSA-9759147 NFE2L2 and MAFG bind the SQSTM1 gene BibTex
2022-02-23 R-HSA-9758090 Ubiquitinated NFE2L2 is extracted from CRL3 complex for degradation BibTex
2022-02-23 R-HSA-9755507 UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex BibTex
2022-02-23 R-HSA-9755505 KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 BibTex
2022-02-23 R-HSA-8932327 NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1 BibTex
2022-02-23 R-HSA-9758088 UBXN7 binds VCP hexamer:UBF1:NPLOC4 BibTex
2022-02-23 R-HSA-9712274 NFE2L2 inducers bind to KEAP1:CUL3:RBX1:NFE2L2 BibTex
2022-02-23 R-HSA-8932355 26S proteasome degrades Ub-NFE2L2 BibTex
2022-02-23 R-HSA-8952631 AcM-UBE2M transfers NEDD8 to CRL3 E3 ubiquitin ligase complex BibTex
2022-02-23 R-HSA-8952630 NEDD8:AcM-UBE2M binds CRL3 E3 ubiquitin ligase complex BibTex
2022-02-23 R-HSA-9762096 Ub,pS335,S338,T NFE2L2 is degraded BibTex
2022-02-23 R-HSA-9762091 NFE2L2 is ubiquitinated by BTRC:SKP1:CUL1:RBX1 BibTex
2022-02-23 R-HSA-9762093 BTRC binds p-S344, 347 NFE2L2 BibTex
2022-02-23 R-HSA-9762094 GSK3B phosphorylates p-NFE2L2 BibTex
2022-02-23 R-HSA-9761836 p14ARF binds NFE2L2:CREBBP, EP300 BibTex
2022-02-23 R-HSA-9761828 NFE2L2 binds the PGD gene BibTex
2022-02-23 R-HSA-9761812 AcK- NFE2L2, MAFG and CREBBP, EP300 bind the G6PD BibTex
2022-02-23 R-HSA-9761846 NFE2L2-dependent PGD gene expression BibTex
2022-02-23 R-HSA-9761830 NFE2L2 binds the TALDO1 gene BibTex
2022-02-23 R-HSA-9761858 NFE2L2-dependent TALDO1 gene expression BibTex
2022-02-23 R-HSA-9761852 NFE2L2-dependent TKT gene expression BibTex
2022-02-23 R-HSA-9761834 NFE2L2 binds the TKT gene BibTex
2022-02-23 R-HSA-9761849 AcK-NFE2L2-dependent P6GD gene expression BibTex
2022-02-23 R-HSA-9761844 NFE2L2-dependent IDH1 gene expression BibTex
2022-02-23 R-HSA-9761822 NFE2L2 binds the IDH1 gene BibTex
2022-02-23 R-HSA-9761815 AcK-NFE2L2 and ATF4 bind the SLC7A11 gene BibTex
2022-02-23 R-HSA-9759186 AcK-NFE2L2- dependent NQO1 gene expression BibTex
2022-02-23 R-HSA-9759141 AcK-NFE2L2 and MAFK bind NQO1 gene BibTex
2022-02-23 R-HSA-9759325 NFE2L2 binds the GSTA3 promoter BibTex
2022-02-23 R-HSA-9761818 NFE2L2 binds the GSR gene BibTex
2022-02-23 R-HSA-9759364 AcK-NFE2L2-dependent TXNRD1 gene expression BibTex
2022-02-23 R-HSA-9759332 AcK-NFE2L2 binds the TXNRD1 promoter BibTex
2022-02-23 R-HSA-9760128 AcK-NFE2L2-dependent GSTA1 gene expression BibTex
2022-02-23 R-HSA-9760097 AcK-NFE2L2 and MAFK bind the GSTA1 gene BibTex
2022-02-23 R-HSA-9759176 NFE2L2-dependent HMOX1 gene expression BibTex
2022-02-23 R-HSA-9759137 NFE2L2 and MAFK bind the HMOX1 gene BibTex
2022-02-23 R-HSA-9761841 AcK-NFE2L2-dependent SLC7A11 expression BibTex
2022-02-23 R-HSA-9761843 NFE2L2-dependent GSR gene expression BibTex
2022-02-23 R-HSA-9759356 NFE2L2-dependent GSTA3 gene expression BibTex
2022-02-23 R-HSA-9760125 AcK-NFE2L2-dependent GCLM gene expression BibTex
2022-02-23 R-HSA-9760103 AcK-NFE2L2 binds the GCLM gene BibTex
2022-02-23 R-HSA-9760122 AcK-NFE2L2-dependent GCLC gene expression BibTex
2022-02-23 R-HSA-9760099 AcK-NFE2L2 binds the GCLC gene BibTex
2022-02-23 R-HSA-9759154 TRIM21 ubiquitinates SQSTM1 BibTex
2022-02-23 R-HSA-9766656 RBX1:CUL3 dissociates from forming autophagosome BibTex
2022-02-23 R-HSA-9755304 MUL1 ubiquitinates UBXN7 BibTex
2022-02-23 R-HSA-9755306 ub UBXN7 is degraded by the 26S proteasome BibTex
2022-02-23 R-HSA-9761900 HBV X protein binds SQSTM1 oligomer BibTex
2022-02-23 R-HSA-8956099 VHL:EloB,C:NEDD8-CUL2:RBX1 complex binds UBXN7 BibTex
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